The Utilita Arena will host night 15 of the competition on Thursday, May 12, 2022.
Joe Cullen will make his Cazoo Premier League debut in 2022, with the eight-player line-up confirmed for this year's new-look tournament.
Cullen's selection came within 24 hours of lifting his maiden TV title at The Masters, while world number one Gerwyn Price and world championship runner-up Michael Smith return to the elite competition after missing the 2021 season.
Heading up the class of 2022 are the world's top three box-office stars Price, world champion Peter Wright and five-time Premier League winner Michael van Gerwen, as well as reigning champion Jonny Clayton.
Former Premier League winners James Wade and Gary Anderson complete the star-studded line-up for the new season in which a £1m prize is up for grabs.
Tickets priced from £30.10 are now on sale. Go to www.utilitaarenasheffield.co.uk