The Spireites said they will be making no further comment until an investigation has taken place.
Rowe was appointed manager in November 2020 after moving from Gloucester City.
First-team coach Danny Webb will take charge for now.
Here’s what Town fans have been saying online since the shock news broke this afternoon...
@spireriteblue39 posted: “This doesn’t look good does it?? Guess time will tell.
@RaggedGray said: “Nightmare. What on earth has happened?”
@hoskin_liam wrote: “Wow. January and top of the league and then a few bad results and this. Could derail our season if we have to look for a new manager.”
@hollybaconnn added: “It is never, ever dull supporting this football club.”
@Sifdog88 wrote: “If this is an internal investigation it must be sorted immediately. We do not need this at this point of the season.”
@ASJD30 wrote: “Whatever has gone on, it needs sorting ASAP. Within days. Or we risk losing all momentum, and gates back to 3k. I’ve never known a manager suspended and come back. Massive few days ahead.”
@lukeCFC25 posted: “Whatever has happened, now is the time to SUPPORT THE TRUST. We will not get out of this league if we let things ruin our season.”
@willstrauss said: “Oh well, it was fun while it lasted.”
@LilTigz wrote: “What the hell is going on! Hope this doesn’t spoil things.”