Derbyshire Roads Policing Unit have made motorists aware of the incident on Twitter.
Traffic is said to be moving slowly in the area as the clean up operation gets underway.
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Posting pictures of the scene on Twitter, Derbyshire Roads Policing Unit said: “Insecure load - bricks slid off the bed and now blocking the road. Why we try and stop as many as we can. ‘It's never come off before’ excuse doesn't wash. #SaferLoads.”