Caldwell makes two changes for first game in charge
Tom Anderson is still recovering from a concussion and misses out, while Kristian Dennis drops to the bench.
Coming into the side are Rai Simons and Gboly Ariyibi.
Simons is likely to partner Ched Evans up front.
For the visitors, in form striker Tom Elliott didn’t travel, along with fellow forward Lyle Taylor.
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Hide AdMidfielder Paul Robinson is suspended and Alfie Egan will make his full Football League debut in the centre of the park.
Chesterfield: Fulton, O’Neil, Donohue, Evatt, Hird, Ariyibi, Gardner, Nolan, O’Shea, Simons, Evans. Subs: Allinson, Ebanks-Blake, Martinez, Beesley, Dennis, Mitchell, Maguire.
AFC Wimbledon: Shea, Fuller, Kelly, Charles, Robertson, Whelpdale, Beere, Reeves, Egan, Barnett, Poleon. Subs: McDonnell, Bulman, Oakley, Francomb, Kaja, Owens, Sibbick.
Referee: Eddie Ilderton.
Assistants: Anthony Moore, Robert Atkin.