Police are appealing for information after the visitor centre at Kedleston Hall was broken into.
Sometime between 5pm on Thursday, July 30 and 9.45am on Friday, July 31, offenders forced a rear ground floor window to gain entry to the visitor centre at the National Trust property near Quardon.
They made a search of the building before breaking into a safe and stealing cash.
Anyone with information is being urged to contact PCSO Paula Bennett from the Quarndon and Kirk Langley Safer Neighbourhood Team quoting crime number 32421/15.
To report crime anonymously call Crimestoppers on 0800 555 111.