All emergency services including the air ambulance were sent to a Dronfield crash.
The one-vehicle crash happened last night, Friday, February 16 at around 11.30pm.
A spokesman for Derbyshire Fire and Rescue said: “A crew from Dronfield attended a road traffic collision involving one vehicle on Bowshaw, Dronfield.
“They gave trauma care & assisted the Yorkshire Ambulance Service with one male casualty before his conveyance to hospital.
“One female casualty received medical care from ambulance personnel.
“Derbyshire Police and the helimed also attended.”