Six vehicles were seized during a targeted police operation in Shirland last week.
Safer Neighbourhood officers teamed up throughout the day on Thursday to carry out vehicle safety checks on the A61.
During the Operation Safedrive event, 50 vehicles were stopped as officers cracked down on offences such as motorists not wearing a seatbelt, using a mobile phone at the wheel and vehicle defects.
Twelve motorists were stopped for not wearing a seatbelt, two for using a mobile phone and one for speeding.
Warnings and penalties were issued to 14 people for vehicle registration plate offences, and 15 motorists for issues such as defects with tyres, lights and brakes.
Six vehicles were seized as they had serious defects which stopped the driver continuing their journey without repair or recovery of the vehicle.
HM Revenue and Customs also carried out fuel checks on diesel vehicles.
Safer Neighbourhood Sergeant Leslie Rawson said: “The point of Operation Safedrive is to make our roads as safe as we can for drivers, passengers and pedestrians.
“We will continue to work alongside our partners to promote the message of road safety and vehicle maintenance, and those motorists who put others at risk will be dealt with appropriately.”